Alzheimer's Disease Linked to Altered 3D Genome Organization
A new study reveals that the 3D organization of DNA is disrupted in brain cells affected by Alzheimer's disease, altering gene activity.
A new study reveals that the 3D organization of DNA is disrupted in brain cells affected by Alzheimer's disease, altering gene activity.
Bat DNA reveals a strong link between longevity and immune function, showing longer-lived bats have more cancer-fighting genes and unique cell damage responses.
Scientists discovered that alcohol-damaged livers may fail to regenerate due to inflammation-driven RNA errors, trapping cells in a non-functional state and suggesting new treatment targets.
New research using ancient DNA and dental calculus reveals that the human aversion to eating insects in Europe may stem from a 9,000-year evolutionary history, contrasting with more common insect consumption in tropical regions and among Neanderthals.
Researchers used AI to decode a key DNA sequence, known as the "initiator," which acts as an "on switch" for human genes, found in about 60% of genes.
Galápagos giant daisies have repeatedly evolved similar leaf shapes for heat tolerance using different genetic tools, with new species potentially forming.
Galápagos giant daisies have repeatedly evolved similar heat-tolerant leaf shapes using different genetic pathways, demonstrating parallel evolution.
Ancient DNA from China's 4,000-year-old Shimao city reveals its population's local origins, distant genetic ties, and organized patrilineal kinship. The study also found that most sacrificial victims were male, challenging previous assumptions and offering insights into early East Asian state formation.
A new study reveals that cancer-linked mutations found in immune cells may contribute to Alzheimer's disease, suggesting new diagnostic and treatment avenues.
New research indicates genetic variants may cause GLP-1 drug resistance in about 10% of the population, impacting Type 2 diabetes treatment effectiveness.
Scientists used DNA from museum specimens to identify the extinct Seychelles crocodiles as an isolated population of saltwater crocodiles, solving a 250-year-old mystery.
A new genetic study of over 3,200 Japanese individuals reveals a previously overlooked third ancestral group, challenging existing theories and linking ancient DNA to modern health conditions.
RIKEN researchers identified the ngly2 gene responsible for an acid-active deglycosylating enzyme in fish embryos and determined its molecular structure, suggesting its role in aquatic adaptation.
New research suggests that a father's lifestyle, including exercise and diet, can epigenetically influence offspring traits through specific RNA molecules in sperm.
Scientists transferred a longevity gene from naked mole rats to mice, increasing high molecular weight hyaluronic acid, extending lifespan, and improving health.
A new AI-powered computational method, SpaMosaic, unifies fragmented cell data into comprehensive spatial atlases, accelerating the mapping of the body's cells and predicting unmeasured molecular layers.
Scientists discovered a microscopic pond organism with a unique genetic code, reassigning stop signals and challenging assumptions about gene translation.
University of Pennsylvania researchers developed a new AI method, "Mollifier Layers," to solve complex inverse partial differential equations, improving stability and reducing computational demands.
Scientists are close to reconstructing Leonardo da Vinci's genetic profile by tracing his family lineage and identifying living male descendants, potentially revealing biological insights into his genius.