Vanderbilt researchers developed two new compounds to study the TAOK protein family, linked to Alzheimer's disease, potentially revealing new disease mechanisms and treatment strategies.
Researchers have found that misfolded insulin proteins may contribute to diabetes progression, suggesting new treatment strategies by strengthening cellular protein-folding machinery.
Scientists have identified a biological tipping point in microglial behavior that may determine whether Alzheimer's pathology leads to dementia, offering new treatment targets.
A large study found that updated COVID-19 vaccines continue to provide significant protection against cardiovascular disease, especially for older adults and those with underlying conditions.
Scientists at ETH Zurich identified a new Alzheimer's trigger and developed an experimental compound that slowed nerve cell loss and extended lifespan in mice.
New research indicates genetic variants may cause GLP-1 drug resistance in about 10% of the population, impacting Type 2 diabetes treatment effectiveness.
New nanoparticles inspired by lung fluid can deliver drugs directly to diseased lung tissue, reducing doses and side effects for respiratory conditions.
Scientists have discovered a molecular switch involving the STING protein that drives brain inflammation in Alzheimer's disease, offering a new target for treatments.
Researchers developed a nasal spray that reversed brain aging and improved memory in test models by reducing inflammation and restoring cellular energy.
Graphene quantum dots show promise in preventing the protein clumping linked to Parkinson's disease and other neurodegenerative conditions, according to new research.
New research suggests that vitamin D2 supplements may unexpectedly lower the body's levels of the more effective vitamin D3, impacting immune function.
Scientists have identified the enzyme IDOL as a potential new target for Alzheimer's treatment, finding that its removal from neurons significantly reduced amyloid plaques and improved brain resilience in lab studies.
CAR T-cell therapy, a cancer treatment, is being explored for autoimmune diseases like multiple sclerosis, aiming to reset the immune system by targeting specific cells.
New neuron imaging research has uncovered an unconventional protein transport route called transcytosis, vital for synaptic communication and nerve function.
A new study suggests vitamin B2 may help cancer cells survive by protecting them from programmed cell death, and a related compound, roseoflavin, could trigger this cell death.
A new "Trojan horse" drug for obesity and type two diabetes shows promise in mouse studies, delivering a metabolic enhancer directly to cells for improved weight loss and blood sugar control.
A clinical trial found that nine weeks of immunotherapy before surgery kept specific colorectal cancer patients cancer-free for nearly three years.
A new injectable biomaterial can travel through the bloodstream to repair damaged tissue, reducing inflammation and promoting healing in animal studies.
A new study reveals that the amino acid arginine can significantly reduce toxic amyloid protein buildup and inflammation in animal models of Alzheimer's disease.
Researchers discovered that boosting a protein called Sox9 helps the brain's astrocytes clear Alzheimer's plaques and preserve cognitive function in mice.
A newly identified virus within a common gut bacterium shows a strong link to colorectal cancer, suggesting viruses in microbes may influence disease risk.
A routine blood test marker, the neutrophil to lymphocyte ratio, may predict a person's risk of developing Alzheimer's disease years before symptoms appear, suggesting immune cells could play a role in the disease's progression.